Dot torture is a pretty reasonable drill and takes 50 rounds.
pistol-training.com » Dot Torture
Stress inoculation and adrenaline/cardio are related but different. Simunitions with pain penalties (ie, not so padded up that if you get hit it doesn't hurt) is, IMO, the best stress inoculation outside of real life events. It's not so much the adrenaline as the mental strain of trying to observe, think, plan, execute, etc. all at the same time. Just breathing hard doesn't simulate that, although still a worthwhile skill to have.