The rule for VG's, Vmax, and Blitzkings is usually, "The faster the bullet, the better the result." As long as your rifle can handle it, keep your velocity near max charges.
Obviously every rifle has it's preference in powder. If this is an AR platform, back the powder off a little to save gun wear. If it's a bolt gun, spank those bullets.
Good luck testing. These loads may work, or you may find other loads that work better. It's all up to you.