I won't bad mouth the 458 or the 50. I went with the 450 because at the time ammo was easier to come by. I've put 5 deer down with it since purchasing in 2013.
Five separate people have killed deer with mine. I Had one go around 60 yards on a heart shot but most have not made it farther than a few yards. Put in the lung area they don’t go far.
Word. Ours has performed 100% every deer season. The LGS had/has ammo and I could find barrels way back... It hits hard and is accurate. In 2017, after the heavy rains opening Saturday, my Son and I were hunting that Sunday afternoon... An 8 pointer walked in from behind us. My Son ranged him at 156. Put one in just behind his shoulder. He stumbled around like a drunk. My Son said, put another one into him. Bang- plop.
... And Santa is bringing me a set of 450 dies for Christmas! Looking forward to trying some Barnes solid coppers. I'm hoping they are like the Barnes Tac TX 110gr for 300BO on steroids.
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