No way you're going to have enough on-game energy to ethically hunt with Trail Boss.
.357 and Trail boss: No, not for deer hunting.
125gr XTP with H110: You're halfway there, bump that bullet to a 158gr XTP or a 180gr XTP. A 170-190gr hard cast lead semi-wad cutter will probably work just as well, people that like holes on both sides of the deer say they work better.
Use the start load and work up.