I would guess no, but call the manufacturer to find out for sure. I can tell you that no one that I can find makes one that will fit my Rock Island 22TCM. [FONT="]NRA Life member [/FONT][FONT="]GSSF member[/FONT][FONT="] Gunsite graduateCertified Glock armorer[/FONT] [FONT="] [/FONT][FONT="]1911 Mechanic[/FONT]
Probably not. You say "go in the frame"....so you are likely talking about a LaserMax Guide Rod laser. It replaces the guide rod that's in your gun. LaserMax no longer makes a guide rod laser for any 1911 but, when they did, they were pretty specific about what models it would match up with. In addition to replacing the guide rod, you also have to replace some other part of the gun so that you have a way to turn the laser on and off. With a Sig, for example, you replace the take-down lever and the on/off switch is built into the lever. It's that part that makes it likely that a LaserMax guide rod laser you found for a 1911 won't work in your GSG.
And, if you decided to get one of the grip replacement options, you would have to do some work on the Ambi-Safety to get everything to fit and function...