I have a ADVANTAGE conversion for my glock Advantage Arms Secure Online Store: Glock Conversion Kits and for the other lady looking for a 22LR pistol, I like shooting my accurate RUGER MARK III'm also in the market for a 22 to practice with. Since I carry a Glock 26, it's been difficult to find something similar to it.
I do not like the Walther P22, they are too small.
I shot a GSG1911-22 the other day though it is nothing like my Glock, the 1911 style intrigued me. I would have to get used to the safety on the backstrap, which I got caught not compressing hard enough a couple of times. It also seemed to throw some powder residue back at me as it cycled, so I'm not as convinced as I was on that one.
I like the Ruger Mark III. My husband has a Ruger Single Six and it is extremely accurate, but the Ruger Mark III is nothing like my Glock.
I have held a M&P22 and it felt the most like my carry gun. If I was going to buy one tomorrow this would be the gun. I know that doesn't really answer the OP's guestion, but those are this lady's opinions on the 22LR's I've been around and the reasons I like or don't like them.
I have a Ruger Mark III. it shoots accurate and smooth. it is a pain to clean.
I have a ADVANTAGE conversion for my glock Advantage Arms Secure Online Store: Glock Conversion Kits and for the other lady looking for a 22LR pistol, I like shooting my accurate RUGER MARK II
I have the same problem with working the slides on some semi-autos.Lucky I was able to work the slide on the PX4 Audie purchased for me .I have a Taurus 22 mag revolver. I have not shot it yet. I am actually thinking of selling it so I can get another gun. I had a Walther p22 but it was too hard for me to pull the slide back so I sold it. Good luck with finding what you like and want.
While I am not a lady, my wife likes the feel of my Bersa Thunder 22. Its the size of a 380 and has been accurate and trouble free. It shoots the CCI mini mag 40 grain solids the best.