As you can probably tell, I'm a fan of Alliant smokeless powders.
I used some of Alliant's Power Pistol in some hot jacketed loads for my .357. It really burns clean and I get a lot of velocity for not too high of pressures.
Huge +1! H110 is dirty no matter how I load it and TONS of unburned powder, lots of flash, MEH!
With that bullet, Disposable Heart, hit the nail on the head with Unique.I'm shooting with a 6 inch .357 gp100.I shoot lead 140gswc. Thanks for all advice folks! It sounds like ya'll know your powders. Can't wait to try some out.